Garlic Extract

Information

Information

Garlic Extract

Overview

Garlic extract is a supplement derived from garlic, known for its potential health benefits, including cardiovascular support, immune system enhancement, and antioxidant properties. Historically, garlic has been used for centuries in traditional medicine across various cultures. It is classified as a dietary supplement and is available in different forms, such as aged garlic extract, garlic oil, and garlic powder[1][2].

Forms and Variations

Garlic extract comes in several forms, each with distinct characteristics:

  • Aged Garlic Extract (AGE): Produced by soaking garlic in an alcohol bath for several months, resulting in a water-soluble, odorless extract rich in S-allylcysteine[1][4].
  • Garlic Oil: Contains fat-soluble compounds like diallyl disulfide, obtained through steam distillation or solvent extraction[3].
  • Garlic Powder: Made from dried garlic, often used in capsules, with varying content depending on processing methods[4].

Dosage and Administration

The typical dosage of garlic extract ranges from 200 to 400 mg per day, often taken once or twice daily. For optimal absorption, it is recommended to take garlic extract with meals. Consistency is key, as benefits may take several weeks to manifest[2].

Scientific Research and Mechanism of Action

Garlic extract contains bioactive compounds …

Garlic Extract

Overview

Garlic extract is a supplement derived from garlic, known for its potential health benefits, including cardiovascular support, immune system enhancement, and antioxidant properties. Historically, garlic has been used for centuries in traditional medicine across various cultures. It is classified as a dietary supplement and is available in different forms, such as aged garlic extract, garlic oil, and garlic powder[1][2].

Forms and Variations

Garlic extract comes in several forms, each with distinct characteristics:

  • Aged Garlic Extract (AGE): Produced by soaking garlic in an alcohol bath for several months, resulting in a water-soluble, odorless extract rich in S-allylcysteine[1][4].
  • Garlic Oil: Contains fat-soluble compounds like diallyl disulfide, obtained through steam distillation or solvent extraction[3].
  • Garlic Powder: Made from dried garlic, often used in capsules, with varying content depending on processing methods[4].

Dosage and Administration

The typical dosage of garlic extract ranges from 200 to 400 mg per day, often taken once or twice daily. For optimal absorption, it is recommended to take garlic extract with meals. Consistency is key, as benefits may take several weeks to manifest[2].

Scientific Research and Mechanism of Action

Garlic extract contains bioactive compounds such as S-allylcysteine and diallyl disulfide, which contribute to its health benefits. These compounds have been shown to have antioxidant, anti-inflammatory, and cardiovascular protective effects[3]. The mechanism involves enhancing immune function, reducing oxidative stress, and modulating lipid profiles[2].

Benefits and Potential Uses

Garlic extract is associated with several health benefits:

  • Cardiovascular Health: May help lower cholesterol and blood pressure[3].
  • Immune System Support: Can reduce the incidence and duration of common colds[2].
  • Antioxidant Properties: Helps protect against oxidative stress and inflammation[3].

Side Effects and Risks

Common side effects include indigestion, heartburn, and nausea. High doses may cause gastrointestinal discomfort. There are no known fatal overdoses, but excessive consumption should be avoided[2].

Interactions and Precautions

Garlic extract may interact with blood thinners and diabetes medications. Individuals with bleeding disorders or those undergoing surgery should consult a healthcare provider before use[2].

Impact on Biomarkers

Garlic extract may influence biomarkers related to cardiovascular health, such as cholesterol levels and blood pressure. It can also affect markers of oxidative stress and inflammation[3].

Overdose and Toxicity

While there are no reported cases of fatal garlic overdose, excessive intake can lead to gastrointestinal issues. The water-soluble compounds are generally safe, but fat-soluble compounds may accumulate in the body[2].

References

  1. Diversity of constituents in aged garlic extract and their production. Experimental and Therapeutic Medicine, 2019; 18(6): 4391–4400. https://www.spandidos-publications.com/10.3892/etm.2019.8393
  2. Learn About Garlic Extract in 5 Minutes | Feel - Wellness, Reimagined. https://wearefeel.com/en-us/blogs/learn/what-is-garlic-extract
  3. The nutritional value, bioactive availability and functional properties. Frontiers in Nutrition, 2023; 10: 1142784. https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1142784/full
  4. The Joy of Garlic | Penn State University. https://www.psu.edu/news/research/story/joy-garlic

Disclaimer

The information provided in this document is for educational purposes only and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.

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